A thought-provoking case study of Emily Gavigan’s experience of antibody mediated psychosis is provided in this documentary. Initially Emily was diagnosed with schizophrenia but experienced symptoms which did not fit with schizophrenia. In particularly, she recounts one day where she was not able to walk. Doctors did not understand what was wrong. It was only until she was transferred to the University of Pennsylvania where a previous case of NMDA-receptor antibody encephalitis was diagnosed, was she tested for NMDA antibodies and received a positive result. She received a new treatment in which her immune system was supressed and the NMDA antibodies removed. The treatment was successful, and she began to recover. A short talk by Professor Belinda Lennox is also provided, outlining the results of her study in which almost 10% of a sample of more than 200 people were tested positive for either NMDA antibodies or a similar antibody. She also introduces the SINAPPS study which has the potential to develop new ways of diagnosing and treating those with severe mental illness. The case study begins at 49:51. Unfortunately the episode is no longer available on BBC iPlayer. However a CNN article written after the airing of the programme covers much of the content
Article on Emily Gavigan's experience of antibody mediated psychosis. It covers her struggle with the symptoms and finding an appropriate diagnosis and treatment, and how she came to finally being diagnosed with antibody mediated psychosis. It also covers the work of scientists such as Professor Lennox in the field.
Podcast summary: "We open the series with Carmine Pariante, Professor of Biological Psychiatry at Kings College London. Carmine is at the forefront of research that experts call "one of the strongest discoveries in psychiatry for the last 20 years" – looking at whether our immune system could be causing depression. This understanding could transform the way we treat the condition. Carmine tells us more about this fascinating potential breakthrough and why he thinks the immune system is causing changes in mood". Click here for the website. Podcast is available on Podbean for Android or iTunes store for Apple.